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Case Report
Interesting case of dermatofibrosarcoma protuberance
1 MS, Assistant Professor, Saveetha Medical College, Chennai, Tamil Nadu, India
2 Junior Resident, Saveetha Medical College, Chennai, Tamil Nadu, India
3 Assistant Professor, Saveetha Medical College, Chennai, Tamil Nadu, India
4 MS, Professor, Saveetha Medical College, Chennai, Tamil Nadu, India
5 MD Path, Professor, Saveetha Medical College, Chennai, Tamil Nadu, India
Address correspondence to:
Agil Selvam
M20, Men’s Hostel, Saveetha Medical College, Saveetha Nagar, Thandalam, Chennai 600124,
India
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Article ID: 100083Z12AS2021
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Selvam A, Kothe P, Vinoth M, Rekha A, Ganesh J. Interesting case of dermatofibrosarcoma protuberance. J Case Rep Images Surg 2021;7:100083Z12AS2021.ABSTRACT
Introduction: Dermatofibrosarcoma protuberans (DFSP) is an uncommon soft tissue neoplasm of intermediate to low-grade malignancy. It is a locally aggressive tumor with a high local recurrence but rarely has metastasis. It is a cutaneous malignancy that arises from the dermis and invades deeper tissue (e.g., fat, fascia, muscle, and bone).
Case Report: A 45-year-old male patient presented to the surgery outpatient department with complaints of swelling in the lateral aspect of the left thigh since six months, insidious in onset, gradual in progression. It was associated with pain on walking, sudden increase in size over the last three months. Examination showed swelling of 8 × 5 × 3 cm in anterolateral aspect of left thigh, mobile, mixed in consistency with no peripheral vascular deficit. Ultrasound imaging showed a well-defined isoechoic lesion in subcutaneous plane in anterolateral aspect of left thigh, probably sarcomatous lesion. Trucut biopsy revealed features of spindle cell sarcoma probably fibroblastic. Histopathology examination revealed features of dermatofibrosarcoma protuberance.
Conclusion: In the differential diagnosis of nontraumatic leg pain, tumors, particularly dermatofibrosarcoma should be considered. Magnetic resonance imaging (MRI) is diagnostic and complete surgical resection is curative where recurrence rate is less.
Keywords: COL1A1-PDGFB, DFSP, Morphea-like, Storiform
SUPPORTING INFORMATION
Author Contributions
Agil Selvam - Substantial contributions to conception and design, Acquisition of data, Analysis of data, Interpretation of data, Drafting the article, Revising it critically for important intellectual content, Final approval of the version to be published
Pallavi Kothe - Substantial contributions to conception and design, Acquisition of data, Analysis of data, Interpretation of data, Drafting the article, Revising it critically for important intellectual content, Final approval of the version to be published
Vinoth M - Drafting the article, Final approval of the version to be published
Arcot Rekha - Substantial contributions to conception and design, Acquisition of data, Analysis of data, Interpretation of data, Drafting the article, Revising it critically for important intellectual content, Final approval of the version to be published
Jaya Ganesh - Analysis of data, Interpretation of data, Revising it critically for important intellectual content, Final approval of the version to be published
Guarantor of SubmissionThe corresponding author is the guarantor of submission.
Source of SupportNone
Consent StatementWritten informed consent was obtained from the patient for publication of this article.
Data AvailabilityAll relevant data are within the paper and its Supporting Information files.
Conflict of InterestAuthors declare no conflict of interest.
Copyright© 2021 Agil Selvam et al. This article is distributed under the terms of Creative Commons Attribution License which permits unrestricted use, distribution and reproduction in any medium provided the original author(s) and original publisher are properly credited. Please see the copyright policy on the journal website for more information.
